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Foot & Ankle Specialist, Vol. 1, No. 2, 93-96 (2008)
DOI: 10.1177/1938640008315350

Clinical Research: A New Concept in the Topical Treatment of Onychomycosis With Cyanoacrylate, Undecylenic Acid, and Hydroquinone

Paul Rehder, MD, FAAP, FAAD

Tim T. Nguyen, DPM

The authors report a pilot study of a new approach for the topical treatment of onychomycosis using physiologic principles of fungal growth and serial debridement. In total, 154 patients were studied for 1 year with mild, moderate, and severe nail disease. Negative mycologic cultures in these 3 groups were 100%, 65%, and 35%, respectively. All patients reported subjective improvement in the first 3 months.

Key Words: nail fungus • onychomycosis • cyanoacrylate • undecylenic acid • hydroquinone


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